Select Gut Microbiota Impede Rotavirus Vaccine EfficacySummary
Background & Aims: The protection provided by rotavirus (RV) vaccines is highly heterogeneous among individuals.We hypothesized that microbiota composition might influence RV vaccine efficacy.Methods: First, we examined the potential of segmented filamentous bacteria (SFB) colonization to influence RV vaccine efficacy in mice.Next, we probed th